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Glossary Treatment

Collagenase clostridium histolyticum

Also known as CCH Xiapex Xiaflex

Injectable bacterial collagenase used to lyse Dupuytren cords without open surgery. Marketed as Xiaflex (US, Asia-Pacific) and Xiapex (EU). Withdrawn from the European market by the marketing authorisation holder in March 2020 and discontinued in New Zealand in 2019. Remains an examination topic and a literature comparator.

Articles mentioning this term

  1. FESSH preparation

    Dupuytren's disease

    An expert synthesis of Dupuytren's disease — anatomy, the McFarlane cord pattern, the contemporary treatment landscape after the European withdrawal of collagenase, and the parallel consensus definitions of recurrence — for FESSH candidates and consultant peers.

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